Layout Image
Layout Image
Engineering on the front-line of medicine
Layout Image

The Centre for Medical Image Computing

Layout Image

The Centre for Medical Image Computing

History
The Centre for Medical Image Computing (CMIC) was formed in January 2005. Dave Hawkes, Derek Hill and David Atkinson moved to UCL and joined with Andrew Todd-Pokropek in Medical Physics and Simon Arridge and Daniel Alexander in Computer Science. In 2007 Sebastien Ourselin joined the group as Reader in Medical Image Computing. Since then Brian Hutton of the Institute of Nuclear Medicine, Louis Lemieux, Chris Clark and Xavier Golay of the Institute of Neurology have become Associate mambers, creating a group of researcheers including research fellows, post doctoral research associates, reseaarch assistants and PhD students as of May 2008.

Our Mission
We see CMIC’s work as a key component of the translational pipeline of information from imaging methodology arising in mathematics, computer science, physics, chemistry and the engineering disciplines to biomedical sciences and healthcare. Close working with our clinical colleagues not only provides us with the means to translate new ideas in computation, informatics and imaging into the clinic, but also creates the environment in which new questions are asked and new problems posed that we can feed back into the development of fundamental new methodology. We operate a matrix structure with orthogonal streams of fundamental methodological development and application orientated research. This allows methodology to feed into many applications, each of which can draw on a wide range of methodological expertise. Our close links with industry, including large multinational imaging companies, the pharmaceutical industry and a vibrant community of local SMEs, including our start-ups IXICO and Sageta, allows us to create solutions that can be widely disseminated in healthcare and bio-science.

Fund raising
Our first three years at UCL were dominated by successful efforts to secure short and medium term funding for the group. We were awarded 4 grants in breast cancer (1 large EPSRC project with Oxford, Manchester and ICR; a TSB grant with Carestream – previously Kodak, a TSB grant with Dexella on digital tomosynthesis, and an EU grant as part of the Visual Physiological Human programme (VPH)). We are building our activity in the treatment of liver metastases through a major investment by EPSRC in High Intensity Focussed Ultrasound (with Mechanical Engineering (PI Nader Saffiri) at UCL, ICR and Oxford) and an EU grant as part of the VPH programme. We have a substantial project in colon cancer with industrial and NIHR funding. We have continued to raise funds for collaborations with the Institute of Cancer Research and with Oxford building on the successful MIAS-IRC of which CMIC was a partner and for the last four years Dave HAwkes was Director. We have also continued several collaborations with Guy’s and St. Thomas’ Hospitals (radiotherapy, breast surgery, cardiology, dentistry). We have been awarded 5 TSB grants as part of their Technology Programme, have 4 grants awarded under the EU FP7 programme, and a significant portfolio of research income from EPSRC including a Platform Grant. Our income is running at about £4M pa.

Personal Achievements by CMIC members
Dean Barratt was awarded a Royal Academy of Engineering/ EPSRC Research Fellowship in 2006. Professor Hawkes gave the Willhem Conrad Roentgen Honorary Lecture at the ECR in Vienna in 2006 and the Crookshank Lecture at the FRCR in May 2008. He co-chaired Medical Image Computing and Computer Assisted Interventions (MICCAI) 2009 and was elected Fellow of the MICCAI Society.  MArta Betcke was awarded an EPSRC Maths Fellowship in 2010.  Daniel Alexander was was awarded an EPSRC Leadership Fellowship in 2009 and was appointed as Associate Editor for the IEEE TMI journal. Sebastien Ourselin was appointed Associate Editor for IEEE TMI and MedIA. He was also elected board member of the MICCAI Society. We were delighted and very proud that international conference prizes were awarded to the following PhD students: Tim Carter (MIAR in 2006), Irina Waechter (AAPM 2007 and MICCAI  2007). Steve Thompson (conference highlight at the European Association of Urologists annual meeting 2008).

Research Profile
The Centre’s activities are built around a matrix of applications and methodology. Methodological research includes image reconstruction and inverse problems, imaging moving structures, diffusion imaging and tractography, relating image derived information across scale, multi-modal imaging, image registration, data fusion, visualisation, measurement, shape representation and soft tissue motion correction. Our applications range from improving understanding of structural neuroanatomy and its changes during development, healthy ageing and disease, to expanding activity in image guidance technologies including interventional MR in both cardiovascular sciences and neurosciences, image guided neurosurgery, image guided ENT and maxillo-facial surgery, image guided orthopaedic surgery, and image directed focal therapy in the lung, liver and prostate. Learning, parametrising and correction of tissue motion, in particular due to respiration, has emerged as a major area of activity. In November 2008 we performed the world’s first deformable model based image guided breast surgery. In oncology (specifically in breast cancer) we are starting work on how imaging can be used to relate appearances and changes in appearance of specific phenotypes to discoveries of risk factors associated with specific cancer mutations. Digital tomosynthesis is emerging as an interesting technology for reconstructing breast macro-structure and its change over time. "Active Imaging" is an emerging paradigm, led by Daniel Alexander, that links modelling of image formation with microscopic models of structure and is currently being applied to the study of white matter in the brain using DTI MRI.  In April 2010 we were awarded a large grant form the UCL/UCLH CBRC to develop an open source !Imaging Platform" for translational imaging research.

Layout Image
Layout Image Layout Image

Centre for Medical Image Computing - University College London - Gower Street - London - WC1E 6BT - Telephone: +44 (0)20 7679 0221 - Copyright © 1999-2009 UCL. Disclaimer | Accessibility | Privacy | UCL Search | UCL-CS Help