Program to calculate KN-BSI (piecewise normalisation)".

Program to calculate the KN-BSI, based on the papers: Freeborough PA and Fox NC, The boundary shift integral: an accurate and robust measure of cerebral volume changes from registered repeat MRI, IEEE Trans Med Imaging. 1997 Oct;16(5):623-9.

Leung et al, Robust atrophy rate measurement in Alzheimer's disease using multi-site serial MRI: Tissue-specific intensity normalization and parameter selection, NeuroImage. 2010. 50 (2) 516 - 523.

• Dimensions: 3
• Pixel type: Scalars only, of unsigned char, char, unsigned short, short, unsigned int, int, unsigned long, long, float, double

Caveats

• Notice that all the images and masks for intensity normalisation must have the SAME voxel sizes and image dimensions. The same applies to the images and masks for BSI.